Stress does reduce fertility – but only in women, new study suggests

Higher levels of stress are associated with lower odds of conception for women, but not for men, according to new research by Boston University School of Public Health.

The study, which has been published in the American Journal of Epidemiology, used data from the Pregnancy Study Online (PRESTO), an ongoing preconception cohort of North American pregnancy planners that follows couples for 12 months or until pregnancy, whichever comes first. For the new study, the researchers followed 4,769 women and 1,272 men who did not have a history of infertility and had not been trying to conceive for more than six menstrual cycles.

The researchers measured perceived stress using the 10-item version of the perceived stress scale (PSS), which is designed to assess how unpredictable, uncontrollable, and overwhelming an individual finds their life circumstances.

The items referred to the past month, with five response choices ranging from 0 (never) to 4 (very often), up to a total of 40, with a higher total score indicating a higher level of perceived stress. Both partners completed the PSS at baseline, and women also completed the PSS at each bi-monthly PRESTO follow-up. The baseline questionnaires also included a range of demographic and behavioural factors, including race/ethnicity, household income, diet, sleep, and frequency of intercourse.

On average, baseline PSS scores were about 1 point higher among women than men, and the average follow-up PSS scores among women remained fairly constant over the 12 months that they participated in the study.

The researchers found women with PSS scores of at least 25 were 13 per cent less likely to conceive than women with PSS scores under 10. The association was also stronger among women under 35 years old.

The researchers did not find an association between men’s PSS score and the likelihood of conceiving. However, couples in the study were about 25 per cent less likely to conceive when the man’s PSS score was under 10 and the women’s was 20 or higher.

The study’s lead author, Amelia Wesselink, said: ‘Although this study does not definitely prove that stress causes infertility, it does provide evidence supporting the integration of mental health care in preconception guidance and care.’


  • Thank you very much for the article, I read it with great interest. This is very interesting and important research that can provide answers to other questions. Recently in medicine it so happens that doctors are looking for the answer to one question, and find a completely different one. Our body is one interconnected organism, where everything depends on each other. I read about psychological health and how it affects learning – the results were similar – a student who is constantly under stress, less successful, if not properly rested.
    Great article, I recommend it to everyone.
    Student writer for https://papercheap.co.uk

  • Thank you very much for the article, I read it with great interest. This is very interesting and important research that can provide answers to other questions. Recently in medicine it so happens that doctors are looking for the answer to one question, and find a completely different one. Our body is one interconnected organism, where everything depends on each other. I read about psychological health and how it affects learning – the results were similar – a student who is constantly under stress, less successful, if not properly rested.
    Great article, I recommend it to everyone.