Two weeks of inactivity can trigger diabetic symptoms

Just two weeks without much activity can have a dramatic impact on health from which it is difficult to recover, according to researchers who studied overweight older adults at risk of developing Type 2 diabetes.

Not only did an abrupt, brief period of inactivity hasten the onset of the disease and elevate blood sugar levels among pre-diabetic patients, but researchers reported that some study participants did not fully recover when they returned to normal activity for two weeks.

The findings have been published in The Journals of Gerontology.

Chris McGlory, the study’s lead author, said: ‘We expected to find that the study participants would become diabetic, but we were surprised to see that they didn’t revert back to their healthier state when they returned to normal activity.’

Participants were asked to reduce their daily steps to no more than 1000 steps per day, the equivalent of being housebound due to, for example, illness. Their steps and activity were measured using pedometers and specialized activity monitors, while researchers tested their blood sugar levels and took blood samples during the two-week period.

The results imply that seniors who experience periods of physical inactivity from illness, hospitalization and bed rest, for example, are more likely to suffer harmful consequences to their overall health.

Stuart Phillips, who oversaw the research, said: ‘Treatment of type 2 diabetes is expensive and often complicated. If people are going to be off their feet for an extended period they need to work actively to recover their ability to handle blood sugar.’

The research has shown that within days of the onset of inactivity, there are notable reductions in skeletal muscle mass, strength and a rapid onset of insulin resistance, a common feature of type 2 diabetes.


  • OvN

    If resumption of normal activity is inadequate, perhaps exercising with weights is the next logical step for the study.